HK Neopharm Limited is one of the most reliable manufacturers and suppliers of ademetionine butanedisulfonate in China, featured by quality products and good price. Please rest assured to buy ademetionine butanedisulfonate in stock here and get quotation from our factory. Customized orders are welcome.
Ademetionine 1,4-Butanedisulfonate (CAS 101020-79-5) is a physiologically active molecule widely found in human tissues and body fluids. As a methyl donor (transmethylation) and precursor of physiological sulfhydryl compounds (transsulfuration), it participates in key biochemical reactions in vivo.
This product regulates liver cell membrane fluidity via phospholipid methylation and promotes the synthesis of sulfur-containing metabolites during detoxification, effectively preventing intrahepatic cholestasis. It is indicated for intrahepatic cholestasis in pre-cirrhotic and cirrhotic conditions, as well as cholestasis of pregnancy.
Technical Specifications
|
Product Name |
|
|
Synonyms |
1 4-Butanedisulfonate |
|
Characteristics |
A Off-White powder |
|
CAS Number |
101020-79-5 |
|
Assay |
≥98.0% |
|
Formula |
C42H74N12O28S8 |
|
Package |
Technical Package |
|
Storage |
Under inert gas (nitrogen or Argon) at 2-8°C |
|
Structure |
|
Ademetionine 1,4-Butanedisulfonate (CAS 101020-79-5) is a high-purity API for liver disease treatment and a key raw material in intrahepatic cholestasis therapy. Its mechanism restores hepatocyte membrane fluidity and enhances sulfur compound synthesis, laying a solid material foundation for treating cholestasis in pre-cirrhotic, cirrhotic and pregnancy conditions. As reputable China Ademetionine 1,4-Butanedisulfonate manufacturers, we ensure stable supply of high-grade raw material.
Product Features
Ademetionine 1,4-Butanedisulfonate is a high-purity liver disease API that acts precisely on hepatocytes, regulating membrane fluidity through transmethylation with minimal interference to normal physiological pathways, showing high specificity and strong targeting.
This raw material significantly improves intrahepatic cholestasis and promotes sulfur-containing metabolite synthesis during detoxification, providing core pharmacological support for intervention in cirrhosis-related and pregnancy-related cholestasis.
With a clear and definite mechanism, it performs stably in improving liver function and reducing bilirubin levels, offering reliable raw material support for chronic liver disease drug development.
It features excellent formulation compatibility and stable pharmacological activity, suitable for injections, enteric-coated tablets and other dosage forms, making it an ideal raw material for preclinical research and innovative liver drug development.
As a classic liver disease API, it excels in promoting bile excretion and protecting hepatocyte function, providing vital support for intrahepatic cholestasis treatment.
Full-Cycle Quality Control & Consistent Quality
Strict full-process traceability is implemented from starting materials to synthetic intermediates of S-Adenosyl-L-Methionine 1,4-Butanedisulfonate, with all raw materials complying with pharmacopoeia standards to ensure quality consistency from the source.
The entire production adopts online monitoring and key-node quality control, with precise control of reaction parameters to stabilize the process, reduce impurity risks, and guarantee purity and activity.
Finished products are tested via HPLC, LC-MS and other multi-dimensional methods, with purity ≥98.0%. Impurities, moisture, residual solvents and other indicators meet ICH and pharmaceutical-grade API specifications, ensuring full compliance of each batch.
A full life-cycle quality traceability system is established, with regular process verification and stability studies to continuously optimize quality control and ensure stable quality during long-term storage and large-scale supply.
Application Scenarios
With precise hepatic targeting and reliable quality, Ademetionine 1,4-Butanedisulfonate is widely used in innovative drug R&D, clinical production and academic research, providing stable and compliant core raw material support for intrahepatic cholestasis treatment.
It is mainly used in R&D and production of drugs for intrahepatic cholestasis caused by pre-cirrhosis, cirrhosis and pregnancy, serving as a core API to support clinical formulation development and meet clinical therapeutic raw material demands.
It is suitable for drug registration, clinical trials and commercial production by global pharmaceutical enterprises, providing stable upstream raw material support for liver-targeted metabolic liver disease drugs.
It can be used in cutting-edge research on intrahepatic cholestasis and liver fibrosis intervention, offering high-quality experimental raw material for disease mechanism exploration and new therapy development based on its specific mechanism.
It adapts to the global pharmaceutical supply chain, serving R&D institutions, manufacturers and CDMO platforms to meet R&D, pilot and large-scale production demands. We maintain Ademetionine 1,4-Butanedisulfonate in stock for timely supply.
Packaging and Transportation
- Scientific packaging and reliable transportation are essential to maintain the quality of 1,4-Butanedisulfonate raw material. The company strictly follows pharmaceutical raw material storage and transportation standards to ensure full-process safety and control.
- Products use sealed packaging meeting pharmaceutical standards, with moisture-proof inner layers and reinforced outer protection to avoid moisture, contamination and physical damage. Packaging options include 5kg/drum, 10kg/drum, 25kg/drum.
- All inner packages comply with strict cleanliness standards, with complete labeling including product name, batch number, CAS 101020-79-5, expiry date and storage condition (sealed storage below 25℃) for traceability and management.
- Temperature-controlled logistics is used for transportation, with light-proof and shock-proof measures to avoid high temperature and humidity, ensuring product quality remains unaffected. Lyophilized powder injections require intact packaging during shipment.
- Various packaging specifications are available upon customer request, supporting small-batch trial packaging and large-scale industrial supply (1kg aluminum foil bag, 5kg/10kg/25kg fiber drum). We also provide Customized Ademetionine 1,4-Butanedisulfonate packaging solutions.
Our Advantages
Stable Mass Production & Supply Capacity
Focused on large-scale production of Ademetionine 1,4-Butanedisulfonate, we possess mature manufacturing processes enabling long-term stable supply to fully meet customers' full-cycle raw material demands from R&D to industrial production.
Strict Quality Control
In full compliance with pharmaceutical raw material quality standards, our product features outstanding purity (≥98.0%), strict impurity control and excellent batch stability, providing reliable quality support for injection and enteric-coated tablet development.
Flexible Customized Supply Service
With rapid response capability, we offer multi-scale supply including lab, pilot and bulk volumes (5kg/drum, 10kg/drum, 25kg/drum) and support customized demands, effectively shortening customers' new drug R&D and registration cycles. As professional China Ademetionine 1,4-Butanedisulfonate suppliers, we deliver Ademetionine 1,4-Butanedisulfonate made in China with consistent quality.
Comprehensive Compliance & Traceability System
A full-process traceable quality management system is established, with all indicators meeting international pharmaceutical standards (ICH, USP), assisting customers in efficient clinical trials and drug registration.
Professional Technical Support Team
Equipped with an experienced technical and after-sales team, we provide comprehensive technical guidance and prompt response, delivering efficient and professional services in project coordination and quality consultation.
FAQ
Ademetionine 1,4-Butanedisulfonate (CAS 101020-79-5) strictly complies with global pharmaceutical raw material quality control systems with full-process traceability from synthesis to delivery, ensuring stable and reliable quality. As a key API for intrahepatic cholestasis treatment, it meets new drug R&D and commercial production demands, supporting liver disease drug development. With stable supply capacity and comprehensive technical services, we cooperate closely with industrial partners to jointly advance the development of liver disease treatment.
Hot Tags: ademetionine butanedisulfonate, China ademetionine butanedisulfonate manufacturers, suppliers, factory
