HK Neopharm Limited is one of the most reliable manufacturers and suppliers of ubrogepant raw material in China, featured by quality products and good price. Please rest assured to buy ubrogepant raw material in stock here and get quotation from our factory. Customized orders are welcome.
Ubrogepant API is a first-in-class, oral, small-molecule antagonist of the calcitonin gene-related peptide (CGRP) receptor. Unlike previous migraine treatments such as triptans (which are vasoconstrictors), Ubrogepant Raw Material works by selectively blocking the CGRP receptor without constricting blood vessels. This mechanism makes it a crucial therapeutic option for patients with cardiovascular risks who cannot tolerate triptans. It is characterized by rapid absorption and high bioavailability. It's CAS 1374248-77-7.
Technical Specifications
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Product Name |
Ubrogepant API |
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Synonyms |
Ubrogepant Raw Material |
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Characteristics |
A white or off-white powder. |
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CAS Number |
1374248-77-7 |
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Assay |
≥99.0% (HPLC, Subject to the COA) |
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Formula |
C₂₉H₂₆F₃N₅O₄ |
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Package |
Technical Package |
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Storage |
Store at -20℃ |
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Structure |
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The Ubrogepant Raw Material we supply is subject to strict batch-to-batch stability control, making it suitable for formulation development and related research applications.
Product Features

Acute Treatment of Migraine: Indicated for the acute treatment of migraine attacks with or without aura in adults and Ubrogepant purity 99%. We also call it Acute Migraine Treatment API.
Pain Relief: Effectively reduces migraine pain and associated symptoms such as nausea, photophobia (sensitivity to light), and phonophobia (sensitivity to sound).

Mechanism of Action: During a migraine attack, the neuropeptide CGRP is released, binding to its receptor and causing vasodilatation and transmission of pain signals in the trigeminal vascular system. Ubrogepant CAS 1374248-77-7 binds with high affinity and selectivity to the CGRP receptor, competitively inhibiting CGRP from binding. This blocks the downstream signaling cascade, halting the migraine process at the receptor level.
Full-Cycle Quality Control & Consistent Quality
Quality stands as the core competitive advantage of our Ubrogepant Raw Material. We have implemented a full-chain quality management system spanning from raw material sourcing to finished product delivery:

Synthesis Phase:
Leverage advanced synthetic routes with precise control over reaction temperature, time, and raw material ratios to minimize by-product formation at the source.

Refinement & Purification:
Employ multi-stage refining, filtration, drying, and other processes to further purify Ubrogepant API, ensuring compliance with pharmacopoeial and industry purity standards.

Testing & Qualification:
Every batch of Ubrogepant API (CAS 1374248-77-7) is supplied with a full Certificate of Analysis (COA) covering critical parameters such as purity, impurity levels, moisture content, melting point, and more. All data are fully traceable, guaranteeing consistent, uniform batch quality to satisfy the stringent demands of pharmaceutical research and development.
Application Scenarios
The primary applications of Ubrogepant Raw Material (API, CAS 1374248‑77‑7) lie in the development and manufacturing of medications intended for migraine management. Its key usage scenarios are as follows:
Drug Development
Employed in laboratory and pilot‑scale operations, including formulation optimization, manufacturing process improvement and stability evaluation for oral dosage forms.

Industrial Manufacturing
As a validated Ubrogepant API, it enables large‑volume commercial production for certified pharmaceutical firms, delivering essential raw material supply to support the commercialization of finished drug products.
Academic Research
Applied in scientific experiments such as mechanism studies and therapeutic effect validation, driving deeper investigation and advancement of migraine intervention approaches within the pharmaceutical sector.
Packaging and Transportation
To address the hygroscopic and light-sensitive characteristics of Ubrogepant API, we provide bespoke packaging and transport strategies to comprehensively preserve product quality during the entire supply chain.
Packaging Specifications
A wide selection of packaging sizes is provided, with personalized customization available based on client demands, which adequately supports both small-scale R&D tests and future scaled applications of Ubrogepant Raw Material.
Packaging Materials
Pharmaceutical-grade composite films or sealed steel drums with outstanding light-shielding, moisture-resistant and airtight performance are applied. Internal desiccants are added to effectively prevent the powder from absorbing moisture, agglomerating, oxidizing or degrading.
Transportation Assurance
The whole logistics procedure adopts low-temperature and dry-condition transport, minimizing exposure to high heat, strong light and high-humidity surroundings. Extra shockproof and anti-extrusion measures are also enforced to ensure the product is delivered with stable and intact quality.
Our Advantages
Premium Quality & Consistent Manufacturing Standards
We focus on producing high-grade Ubrogepant API with strictly controlled Ubrogepant purity 99% or higher, fully compliant with mainstream pharmacopoeial and pharmaceutical regulatory requirements. Ubrogepant Raw Material manufacturing with reliable, GMP-aligned manufacturing facilities, we ensure stable production processes and batch-to-batch consistency for Ubrogepant Raw Material, making it an ideal choice for Acute Migraine Treatment API development and commercialization. We make sure Ubrogepant Raw Material produced in Chinese facilities.
Highly Competitive & Flexible Pricing
Supported by optimized production routes and long-term stable supply chains, we offer highly competitive pricing for Ubrogepant Raw Material without compromising quality. We provide tiered pricing schemes for R&D trial quantities and commercial bulk orders, maximizing cost efficiency for pharmaceutical enterprises at different project stages.
Reliable Supply & Fast Response Capacity
We maintain safe and sufficient inventory of Ubrogepant API to support prompt order processing. Both small-laboratory batches and large-scale commercial volumes can be fulfilled efficiently, with short lead times to match your project timelines for Acute Migraine Treatment API development and launch.
Professional Quality Control & Full Traceability
Every batch undergoes rigorous testing focusing on Ubrogepant purity 99%, impurity control, moisture, and stability. Complete analytical reports (COA) and traceable data are provided for each delivery, ensuring the material meets strict research, development and registration standards for migraine treatment formulations.
Comprehensive After-Sales & Technical Support
We offer full-range technical services including COA, HPLC spectra, MSDS, regulatory support documents and customized technical consultations. Our professional team provides timely after-sales response and targeted solutions throughout your product development cycle, supporting smooth R&D, registration and commercial production of Ubrogepant API globally.
FAQ
If you are looking to source high-quality Ubrogepant Raw Material CAS1374248-77-7, Ubrogepant API or Ubrogepant powder or buy Ubrogepant Raw Material, please feel free to contact us at any time for an accurate product quotation, technical support and customized cooperation solutions!
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