HK Neopharm Limited is one of the most reliable manufacturers and suppliers of linaclotide capsules in China, featured by quality products and good price. Please rest assured to buy linaclotide capsules in stock here and get quotation from our factory. Customized orders are welcome.
Linaclotide Capsules are globally recognized first‑line oral peptide formulations targeting guanylate cyclase‑C (GC‑C) receptors. Specially developed for irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC) in adults, they feature dual actions of promoting intestinal secretion and visceral analgesia. With nearly no systemic absorption and local targeted efficacy, Linaclotide Capsules demonstrate outstanding safety and serve as core prescription drugs for standardized treatment of chronic constipation and IBS‑C.
As one of the leading China Linaclotide Capsules manufacturers and China Linaclotide Capsules suppliers, we produce Linaclotide Capsules made in China under strict global GMP standards. Clients can buy Linaclotide Capsules with stable quality and competitive Linaclotide Capsules price. We support Customized Linaclotide Capsules and keep Linaclotide Capsules in stock for prompt delivery.
Technical Specifications
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Product Name |
Linaclotide capsules |
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Synonyms |
Linaclotide capsules |
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Characteristics |
White pellet |
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CAS Number |
851199-59-2 |
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Assay |
≥95.0% (HPLC, Subject to the COA) |
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Formula |
C59H79N15O21S6 |
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Package |
Technical Package |
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Storage |
desiccated |
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Structure |
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Focusing on the unmet clinical needs for chronic constipation and constipation-predominant irritable bowel syndrome, the product is manufactured by qualified pharmaceutical enterprises in accordance with global GMP standards, with strict quality control throughout the whole process. It features excellent purity, content uniformity, sterility and stability.
As a highly selective intestinal local GC‑C agonist, it is fully suitable for standardized treatment in gastroenterology outpatient services, chronic disease management and gastrointestinal functional disorders, providing a reliable, mild, long-acting and low-tolerance therapeutic regimen for patients with functional bowel diseases.
Product Features
Precise Peptide Structure, Local High Efficacy
Composed of 14 amino acids in cyclic peptide structure, Linaclotide Capsules are barely absorbed into systemic circulation after oral administration, acting only on intestinal lumen with no systemic side effects, much safer than traditional laxatives and prokinetics.
Dual Mechanism for Radical Treatment
Activates GC‑C to elevate cGMP, promoting Cl⁻/HCO₃⁻ secretion, increasing intestinal fluid, softening stool and accelerating transit; elevates extracellular cGMP to reduce visceral hypersensitivity, relieving abdominal pain, bloating and discomfort effectively.
Stable Physicochemical & Formulation Quality
Mature pellet technology ensures consistent dissolution, accurate dosage and excellent batch uniformity. Fully compliant with pharmacopoeia and ICH guidelines, complete COA is provided to meet clinical and registration requirements.
High Compliance, Long‑Term Friendly
Once‑daily fasting administration, non‑addictive, no intestinal melanosis, no interference with gut flora, suitable for long‑term maintenance therapy for months to years.
Our China Linaclotide Capsules factory guarantees stable Bulk Linaclotide Capsules supply and offers Linaclotide Capsules Free Sample for pre‑order testing, with reliable quality and reasonable Linaclotide Capsules price.
Full-Cycle Quality Control & Consistent Quality
Linaclotide Capsules adopt a full‑chain quality control system covering raw material inspection, pellet preparation, filling and sealing, finished product testing, cold chain storage and transportation, and full traceability, strictly following USP/EP/CP and ICH Q7 standards.
The whole production process is conducted in GMP clean workshops with real‑time monitoring of key parameters to ensure accurate content, controllable related substances, and qualified microbial and endotoxin limits. Each batch undergoes full testing including identification, assay, related substances, dissolution, uniformity and microbial limits, with 100% qualified release.
Complete batch traceability and stability studies are implemented, with continuous process optimization to ensure consistent quality within validity period and support stable global clinical supply.
Application Scenarios
Linaclotide Capsules are widely used in the following core clinical scenarios:
Irritable Bowel Syndrome with Constipation (IBS‑C)
Improve constipation, abdominal pain, bloating and discomfort, increase complete spontaneous bowel movements, recommended first‑line by global guidelines.
Chronic Idiopathic Constipation (CIC)
Gently promote secretion without irritation for patients with poor response to traditional laxatives, difficult defecation, dry stool and incomplete evacuation.
Long‑Term Management of Functional Constipation
Suitable for elderly, non‑organic constipation, sedentary and dietary imbalance populations to improve quality of life.
Gastroenterology Clinical Research
Support clinical observation and combination therapy exploration on gastrointestinal motility, visceral hypersensitivity and gut‑brain axis.
Packaging and Transportation
Pharmaceutical‑grade aluminum‑plastic blister packaging, light‑proof, moisture‑proof and sealed to ensure pellet stability.
Package clearly labeled with product name, specification, batch number, expiry date and storage conditions, fully traceable.
Compliant room‑temperature logistics with 15–30℃ temperature control, shockproof and moistureproof, suitable for long‑distance and cross‑border delivery.
Flexible specifications meet hospital procurement, pharmacy dispensing and long‑term home medication needs.
Our Advantages
GMP Compliant Production, Quality Equivalent to Originator
Full compliance with international pharmaceutical standards, strict impurity control, stable efficacy and safety.
01
Dual Action, Outstanding Clinical Advantages
Combine defecation promotion and pain relief, superior to single‑action prokinetics or osmotic laxatives.
02
Minimal Systemic Absorption, Leading Safety
No cardiovascular, central, hepatic or renal burden; no routine dosage adjustment for elderly or renally/hepatically impaired patients.
03
Stable Supply + Full Documentation Support
Large‑scale capacity ensures delivery; complete registration documents including COA, HPLC, MS and stability data are provided.
04
Once Daily, Excellent Compliance
Convenient fasting administration, high patient acceptance, ideal for long‑term chronic disease management.
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FAQ
If you are engaged in functional constipation or IBS‑C standardized treatment and seek stable supply of high‑quality Linaclotide Capsules with favorable Linaclotide Capsules price, welcome to contact us for cooperation. We provide accurate quotation, one‑on‑one technical support and customized solutions from R&D to commercialization.
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