HK Neopharm Limited is one of the most reliable manufacturers and suppliers of propofol medium and long chain fat emulsion injection in China, featured by quality products and good price. Please rest assured to buy propofol medium and long chain fat emulsion injection in stock here and get quotation from our factory. Customized orders are welcome.
Propofol Medium and Long Chain Fat Emulsion Injection is a first-line short-acting intravenous general anesthetic and sedative agent in clinical practice. Adopting a combined medium-chain/long-chain triglyceride fat emulsion carrier, it features ultra-fast onset, rapid recovery, less injection pain, and safer metabolism. It is one of the preferred intravenous anesthetics for sedation in operating rooms, ICUs, and outpatient procedures, widely used for anesthesia induction, maintenance, and critical care sedation in adult and pediatric patients with high clinical recognition and full coverage of application scenarios.
Technical Specifications
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Product Name |
Propofol Medium and Long Chain Fat Emulsion Injection |
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Synonyms |
Long Chain Fat Emulsion Injection |
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Characteristics |
White or off-white uniform milky liquid |
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CAS Number |
2078-54-8 |
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Assay |
≥99.0% (HPLC, Subject to the COA) |
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Formula |
C12H18O |
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Package |
Technical Package |
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Storage |
Store at 2-8℃ |
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Structure |
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This product takes high-purity propofol as the active ingredient, combined with medium-chain triglycerides + soybean oil composite oil phase, injectable egg yolk lecithin and other excipients. It is produced by high-pressure homogenization sterile emulsion process, with uniform emulsion droplet size, excellent stability, and lower free propofol concentration, which significantly reduces injection pain and lipid accumulation risks from the formulation level. It is produced in strict accordance with GMP sterile standards, pyrogen-free, particle-free, and microbial contamination-free, providing a safe, stable and controllable high-quality preparation solution for clinical anesthesia and sedation.
Product Features
Ultra-fast onset, clean recovery
It takes effect rapidly in 30~40 seconds after intravenous administration with smooth anesthesia induction; fast metabolic clearance without obvious accumulation, rapid recovery after drug withdrawal with clear consciousness recovery, low incidence of nausea and vomiting, improving postoperative comfort and turnover efficiency.
Significantly reduced injection pain, better tolerance
The medium and long chain fat emulsion carrier greatly reduces the concentration of free propofol, significantly relieves intravenous injection pain, and improves patient tolerance. Comfortable administration can be achieved without routine compatibility with lidocaine.
Faster metabolism, friendlier to liver and kidney Medium-chain triglycerides are metabolized rapidly and completely without carnitine-dependent transport. Long-term infusion is less likely to cause hypertriglyceridemia, with less impact on liver fatty infiltration. It is suitable for long-term surgery and continuous ICU sedation, and can also be used in infants and young children.
Excellent sedation and anesthesia, stable hemodynamics
It exerts sedative and hypnotic effects mediated by GABA receptors, with controllable anesthesia depth and relatively stable circulation. It can be used alone or combined with local/regional anesthesia, suitable for general anesthesia induction and maintenance, procedural sedation, and ICU mechanical ventilation sedation in all scenarios.
Wide applicable population, pediatric-friendly
It can be used for anesthesia induction and maintenance in infants, children and adults over 1 month old; for mechanical ventilation sedation in ICU over 16 years old. The formulation is safe and dosage is easy to titrate, meeting the clinical needs of all age groups.
Full-Cycle Quality Control & Consistent Quality
This product implements the highest-level quality control system for injections, with closed-loop control from raw materials, preparation, filling to release:
Strict raw material control
Only propofol, injectable soybean oil, medium-chain triglycerides, and egg yolk lecithin that meet pharmacopoeia standards are selected, and all items are tested before use.
01
Sterile process
Produced in Grade B+A clean area, 0.22μm sterilizing filtration + aseptic filling, with nitrogen protection throughout to ensure pyrogen-free, sterile and particle-free.
02
Emulsion stability
Precisely control emulsion droplet size (90% ＜1μm), eliminate phase separation and large-size droplets, ensuring infusion safety and uniform efficacy.
03
Full inspection and release
Each batch is provided with a complete COA, covering traits, pH, related substances, content, sterility, bacterial endotoxin, emulsion particle distribution and other indicators, with traceable data and excellent batch-to-batch consistency.
04
Stability verification
Through accelerated and long-term storage inspection, the traits, content, related substances and emulsion state are stable and reliable within the validity period under cool storage conditions.
05
Application Scenarios
General anesthesia induction and maintenance:
Used for rapid induction of general anesthesia and smooth intubation in various surgical operations; continuous infusion during operation to maintain anesthesia depth, rapid recovery after drug withdrawal, suitable for outpatient, day surgery and conventional major surgery.
Procedural sedation:
Sedation for short procedures such as endoscopy, intervention, radiology, and stomatology, with fast onset, rapid recovery and clear consciousness, improving patient cooperation and diagnosis and treatment experience.
ICU critical care sedation:
Continuous sedation for mechanically ventilated patients over 16 years old, arousable and easy to evaluate, without significant respiratory depression, relatively stable circulation, suitable for long-term intensive care sedation.
Pediatric anesthesia and sedation:
Anesthesia induction and maintenance for infants and children over 1 month old, dosage titrated by body weight, safe formulation and smooth recovery, suitable for pediatric surgery.
R&D and registration:
Used for generic drug consistency evaluation, formulation process development, BE test, registration application, providing stable reference preparations and complete compliance data support.
Packaging and Transportation
Sterile and safe packaging
Disposable sterile vials/ampoules, light-proof and shock-proof packaging to eliminate pollution and light degradation, ensuring safe clinical use.
Cool storage and transportation
Cool transportation throughout (≤20℃), anti-freezing, high temperature and severe vibration protection to ensure stable emulsion without layering.
Compliant logistics
GSP-qualified pharmaceutical logistics, traceable throughout; complete customs and documents for international transportation to ensure global compliant delivery.
Validity period management
First-in first-out, regular sampling inspection, validity period early warning to ensure clinical and R&D use within the validity period.
Our Advantages
Mature emulsion process, stable quality Adopting the international mainstream medium and long chain fat emulsion formula, sterile, pyrogen-free, uniform emulsion droplets, excellent batch consistency, in line with ChP, USP, EP standards, meeting consistency evaluation requirements.
Outstanding formulation advantages, safer clinical application Low injection pain, fast metabolism, low accumulation, reducing lipid load and liver impact, safer for long-term infusion, suitable for all scenarios of surgery and ICU.
Full specifications in stock, stable delivery time Covering 10ml/20ml/50ml/100ml full specifications, large-scale production capacity and sufficient inventory, rapidly responding to clinical, R&D and commercial orders.
Complete compliance documents, comprehensive technical support Providing COA, MSDS, GMP certificate, stability data, spectrum data, etc., supporting registration application, consistency evaluation and hospital access.
Professional storage and transportation guarantee, worry-free throughout Customized light-proof, shock-proof, sterile packaging + cool cold chain logistics to ensure each batch is stable, safe and effective.
FAQ
If you focus on perioperative anesthesia, ICU sedation and outpatient comfortable medical medication, and are interested in the stable supply and professional supporting services of high-quality Propofol Medium and Long Chain Fat Emulsion Injection, welcome to negotiate cooperation. We provide accurate quotation, one-to-one technical support and customized solutions from R&D trial to commercial supply, providing reliable preparation support for your anesthesia and critical care projects.
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