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NusinersenNusinersen (CAS 1258984-36-9) is the world’s first approved antisense oligonucleotide (ASO) drug for spinal muscular atrophy (SMA), with nusinersen FDA approval for clinical application.read more
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Octreotide APIOctreotide API (CAS 83150-76-9) is a synthetic long-acting somatostatin analog, which is a core polypeptide active pharmaceutical ingredient for anti-tumor and tumor symptomatic treatment.read more
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Lanreotide APIAs a classic long-acting synthetic cyclic octapeptide somatostatin analog, Lanreotide API (CAS 127984-74-1) is refined by solid-phase polypeptide synthesis with high-purity pharmaceutical-grade aminoread more
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Degarelix APIDegarelix (CAS 214766-78-6), a third-generation GnRH receptor antagonist polypeptide Degarelix API, has become an important choice for endocrine therapy of prostate cancer since its launch.read more
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Propofol APIPropofol is a widely used alkylphenol short-acting intravenous anesthetic API. With fast onset, rapid and complete recovery, thorough metabolism and mild adverse reactions, it has become one of theread more
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Milrinone PowderMilrinone Powder is a clinically essential non-glycoside, non-catecholamine phosphodiesterase 3 (PDE3) inhibitor API with dual anti-tumor and cardiotonic effects. Identified by the unique code CASread more
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Lenalidomide APILenalidomide API (CAS 191732-72-6) is a core second‑generation immunomodulatory antineoplastic API in global clinical practice. It combines four core activities: direct tumor cell killing, immuneread more
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Dexrazoxane Raw MaterialDexrazoxane Raw Material (CAS 850140-73-7) is a globally recognized cardioprotective API for chemotherapy, widely used in oncology centers across the world. As a highly effective Dexrazoxane API, itread more
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Afatinib DimaleateAfatinib Dimaleate API (CAS 850140-73-7) is a second-generation irreversible targeted anti-tumor API that delivers broad-spectrum ErbB family receptor blockade and acts as key raw material forread more
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DonidalorsenDonidalorsen API (Donidalorsen CAS 2304692-48-4) is a novel antisense oligonucleotide raw material. By targeting and regulating related gene expression, it provides an innovative intervention pathread more
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Abiraterone Acetate APIAbiraterone Acetate API (CAS 154229-18-2) is a highly potent and selective CYP17 inhibitor API, developed specifically for endocrine therapy of metastatic prostate cancer. It is converted to itsread more
WebJan 19, 2023 · Dosage of nusinersen sodium expressed in terms of nusinersen. Pediatric Patients Spinal Muscular Atrophy Intrathecal Initiate therapy with a series of 4 loading...
WebThe U.S. Food and Drug Administration today approved Spinraza (nusinersen), the first drug approved to treat children and adults with spinal muscular atrophy (SMA), a rare and...
WebExplore the MOA. Data and Safety Profile. SPINRAZA has been studied in the longest SMA clinical trial program to date 3. Discover the Data Safety Profile. Dedicated Patient...
WebNusinersen. More... An antisense oligonucleotide that induces survival motor neuron (SMN) protein expression, it was approved by the U.S. FDA in December, 2016 as Spinraza for the treatment of...
WebSep 12, 2022 · Nusinersen works by helping the body produce a protein essential to the function of nerves that control muscle movement. This protein is lacking in people with an...
WebNusinersen, an antisense oligonucleotide, is administered directly into cerebrospinal fluid. It alters SMN2 pre-RNA splicing so exon 7 is included, increasing expression of functional...
